Tag: Dale Bredesen

Preventing and Reversing Alzheimer’s – Dr. Kat Toups

Dr. Dale Bredesen, author of The End of Alzheimer’s, in an interview podcast with Kirkland Newman, indicated that he was the theoretician oversighting the work of his team engaged in clinical trials to prevent and reverse Alzheimer’s.  He also introduced Dr. Kat Toups as the practitioner and Principal Researcher for the clinical trials.  Kat specialises in functional medicine psychiatry and in 2009 was awarded the honour of Distinguished Fellow of the American Psychological Association (APA), the highest honour bestowed by the APA.  After researching Alzheimer’s for 20 years and working with Dementia patients in her clinic, she found in 2010 that she herself was a Dementia sufferer.  She spent the next three years researching and treating herself to the point where she was able to return to her practice after a period of incapacitation.

Kat was 50 years old at the time of her self-diagnosis of Dementia and she was acutely aware that such early onset Alzheimer’s tends to develop more rapidly than for people who are 65 years or older.  Kat described development of her symptoms as a progressive deterioration of her cognitive abilities:

  • Commencing with her inability to remember two sets of three words that she had used for 20 years in undertaking memory tests with her patients (she had to write them down to access them)
  • She found she was unable to reverse park or parallel park her car because these involved fairly complex cognitive steps
  • Her memory of how to work on her computer declined – she could not  remember how to operate this primary research tool and its particular functions; she found that her husband would get annoyed at her because she could not remember his instructions or that he had actually reminded her of the processes involved
  • Kat found she had difficulty remember phone numbers, and even worse, needed multiple attempts to dial a phone number
  • She found during a conversation at a friend’s place that she lost track of the conversation and was unable to understand what was being said in normal conversation (her cognitive ability had declined to the point where she had developed auditory processing problems)
  • She continued to deteriorate and eventually she suffered extreme fatigue, had difficulty getting out of a chair (for a year) and could not work.

Kat was very conscious of her concurrent problems including an auto-immune disease, Lyme disease, chemical sensitivity, allergy to multiple things resulting in hives and rashes all over her body and brain fog (resulting from exposure to chemicals in stores).  Because of her awareness of the many factors impacting cognitive ability – such as toxins, nutrient deficiency, lack of hormones, lifestyle challenges and stresses, inflammation and infections, and diet – she was motivated to undertake a battery of tests to determine and treat the specific factors impacting her cognitive health.  She indicated that in her clinical trials she does the same thing – isolate personal factors that can then become “treatment targets” for reversing the impact of Dementia (including Alzheimer’s).

Kat was eventually able to return to work and resume her clinical practice with the added benefit, because of her personal experience, of being able to treat her patients faster than she had treated herself.  She explains the thoroughness of her self-testing and treatment in her podcast interview with Kylene Terhune, Functional Diagnostic Nutrition (FDN) practitioner.

In her interview with Kirkland mentioned previously, Kat discussed a case study that demonstrated reversal of Dementia.  She spoke about a patient who had been tested elsewhere at the age of 60 and found to have a delayed memory score of 19, a score that should have been “way over 50”, given his education and obvious intelligence.  When he presented for a Dementia trial with Kat at age 63 (after doing nothing in the intervening period on the basis of the medical advice he had received), his cognitive test result was 7 (a decline of more than 50%).  Kat stated that she and her team were able to reverse this result after the patient spent 9 months in the clinical trial – resulting in a score of 92 at the end of that time.   

Ways to prevent and reverse Alzheimer’s and other forms of Dementia

Kat provides a free e-book, Decoding Dementia, in which she explains the causes of decline in memory and cognitive ability, discusses different treatment options, proposes diet and lifestyle changes and ways to test for and identify underlying causes of Dementia, including toxins (especially mould), inflammation, lack of hormones, and stress.

Kat provides what she terms a Basic Dementia Protocol which includes:

  • Identifying and correcting any underlying causes likely to contribute to cognitive problems
  • Observing her guidelines on exercise, diet and sleep
  • Brain training e.g. Brain-HQ
  • Correcting vision and hearing through testing and taking remedial action
  • Overcoming deficiencies in nutrients (e.g. Vitamin D)
  • Reducing stress by using mindfulness practices
  • Restoring hormones to the right levels and balance.

Kat is particularly conscious of the need to remove mould from homes and correct sleep apnea:

  • Mould – Kat explains that certain types of mould “can result in inflammation and destruction of the neurons” if left unattended over a reasonable period.  She advocates strongly for mold testing using home kits and external professional assessment.  Kat provides detailed instructions on how to go about dust collection and assessment (pgs. 10-11 of Decoding Dementia).
  • Sleep Apnea – Kat encourages testing and correcting Sleep Apnea where frequent snoring occurs as this condition causes a continuous loss of oxygen to both the brain and the heart.  In her words, if left untreated, “Sleep Apnea can lead to both Dementia and Congenital Heart Disease”.

In her free e-book, Decoding Dementia, Kat offers more details in relation to each of the elements of her Basic Dementia Protocol.  On mindfulness, she states that any mindfulness practice will be beneficial provided it is done on a daily basis and, ideally, for at least 20 minutes.  Kat recommends using a mindfulness practice that suits you personally and your commitments.  She encourages the use of guided meditations such as those provided by the Mindful Awareness Research Centre (MARC), UCLA.  Other options Kat proposes include Tai Chi, Gratitude practices including journalling, Meditation apps such as HeadSpace, and HeartMath Technology (focused on inner balance and stress reduction).

Reflection

We can each think of someone who could make use of the information and options provide by Kat.  The challenge is to apply her experience and research insights to ourself and undertake the testing, lifestyle changes and treatments (where necessary) that she proposes.  I find that guided mediations, mantra meditations and Tai Chi (meditation-in-action) are my favourite mindfulness practices.  Through these practices, I hope to grow in mindfulness so that I can increase my self-awareness, develop and support my brain (through improved attention and concentration) and build better understanding and compassion.  I hope to cultivate and savour my subconscious and gain greater access to my innate creativity.

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Image by Gerd Altmann from Pixabay

By Ron Passfield – Copyright (Creative Commons license, Attribution–Non Commercial–No Derivatives)

Disclosure: If you purchase a product through this site, I may earn a commission which will help to pay for the site, the associated Meetup group, and the resources to support the blog.

Note: The Content of this post is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.

Preventing Alzheimer’s – It’s Not What You Think

Kirkland Newman, researcher, writer and philanthropist, has established the MindHealth360 website to make free resources and solutions available to anyone who wants to access information on mental health issues.  She shares her vision of an integrative approach to mental health through her advocacy of functional medicine psychiatry – an approach that does not just look at symptoms but explores root causes of illnesses.  Foundational to her approach is the recognition of the need to integrate our inner life, biochemical elements and lifestyle/behavioural approaches.  Her revolutionary approach to integrative mental health derives from family and personal experiences of disintegrated and injurious pharmaceutical treatments for postnatal depression.  Kirkland discovered the lasting benefits of integrative medicine (also called functional medicine) 11 years after suffering severe postnatal depression and has dedicated herself to sharing the benefit of this approach with others. 

Kirkland’s MindHealth360 website provides a comprehensive discussion of factors that could, in combination, be contributing uniquely to an individual’s mental health issues – these potential contributors have been categorised under the three main areas of lifestyle/behavioural, psycho-spiritual and biochemical factors.  Her documentation of these contributors is enriched by video podcasts of her interviews with leading experts on integrative mental health.  In this post, I want to explore one interview that covers the groundbreaking work of Dr. Dale Bredesen and Dr. Kat Toups on preventing and reversing Dementia (including Alzheimer’s – the most prevalent form of Dementia).  Dale is the author of The End of Alzheimer’s: The First Programme to Prevent and Reverse the Decline of Dementia and The Practical Plan to Prevent and Reverse Cognitive Decline at Any Age.

Misconceptions about the nature of Alzheimer’s

Dale, who is a world-famous neurologist, was at pains to point out that the medical profession has completely misconstrued Alzheimer’s and led people astray into believing that it cannot be prevented or reversed.  His fundamental proposition aligns with Kirkland’s integrative medicine  approach.  He contends, for example, that the medical profession is treating Alzheimer’s as a simple disease rather than a complex one – he likens this perspective to treating Alzheimer’s like playing checkers instead of playing the more complex game of chess.   He argues that even the latest approved FDA Alzheimer’s drug will only slow the symptoms of Alzheimer’s but does not provide improvement.  He suggests that this disintegrated pharmaceutical approach is like fixing one hole in a ceiling riddled with more than 36 holes. 

He argues, based on successful clinical trials with his team, that there are four major areas that contribute to the development of Alzheimer’s:

  1. Inflammation (which can result from multiple different sources such as poor dental care)
  2. Toxins (including air pollution and household mould)
  3. Energetics (a technical term covering aspects such as blood flow, level of oxygen and presence of ketones)
  4. Nerve growth and neuron support (called “trophic support”, the presence of molecules that help neurons to develop and sustain necessary connections) – this includes hormones such as estrogen and testosterone, as well as nutrients such as Vitamin D.

Success in terms of Dale’s team means actually preventing and/or reversing the progress of Alzheimer’s.  The clinical trials of his team provide considerable proof that Alzheimer’s is reversible if you adopt an integrative approach which includes a battery of tests covering the four areas mentioned above and other aspects such as measurement of cognitive impairment (using MRI procedures and the MoCA Cognitive Assessment Test).  Added to these more quantitative approaches is discussion with a patient’s partner to discover whether they have observed any noticeable change in the person being assessed.

Dale argues for this more integrated “cognoscopy” approach and maintains that anyone over 45 years of age should seek out such comprehensive assessment of cognitive impairment.  He maintains that the term “Mild Cognitive Impairment (MCI)” is, in fact, misleading as this condition constitutes an advanced stage of Alzheimer’s (not an early stage as the name suggests).  Dale explains that his team has identified four stages in the development of Alzheimer’s:

  • Phase 1 – No symptoms but impairment detectable on a PET Scan (can occur 20 years prior to assessment of MCI)
  • Phase 2 – Subjective assessment – you know something is wrong but impairment is not detected by standard tests
  • Phase 3 – Mild Cognitive Impairment (MCI) as measured on tests such as the MoCA mentioned above.
  • Phase 4 – Final stage of advanced symptoms that are adversely impacting your daily activities.

Preventing and reversing Alzheimer’s

Dale contends, based on the improvements in Alzheimer’s patients during clinical trials, that Alzheimer’s is reversible particularly if cognitive impairment is identified and addressed in its early stages.  In the trials, the researchers chose people who were assessed as having Mild Cognitive Impairment (that is, with MoCA scores of 19 or less, but not including those in the zero to 5 range).  The results show that 84% of the patients actually improved their cognitive assessment, despite the intervention of the pandemic (a summary of the results is provided at 23.48 mins in the video podcast).

Dale states that a “one size fits all approach” to treatment is totally inadequate because of the considerable variability amongst individuals in relation to the four major areas discussed previously (inflammation, toxins, energetics and nerve/neuron support).  In concert with Dr. Kat Toups, he states that Alzheimer’s is also preventable if we look to maintain our health holistically having regard to the key lessons identified from their personal experience, research and clinical practice. 

Reflection

These insights on Alzheimer’s, developed through evidence-based trials, remind us of the need to access the wisdom of the body and to consciously adopt a self-care plan.  It also means that it is desirable to be proactive in obtaining professional assessments of our physical and mental health.  Kirkland reminds us that we need to attend to our “inner life”, especially negative thoughts and beliefs that over time can result in the release of stress hormones that “can cause further hormone and neurotransmitter imbalances”.   She argues for the use of meditation and mindfulness to manage our thought patterns and beliefs, as these improve self-awareness and self-regulation.

We can explore our inner landscape as we grow in mindfulness through Tai Chi, mantra meditation, yoga or other mindfulness practices.  Kirkland contends that mindfulness can help us to develop emotional regulation as we become aware of our thought-feelings patterns and learn to break the habit loop.

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Image by Mirosław i Joanna Bucholc from Pixabay

By Ron Passfield – Copyright (Creative Commons license, Attribution–Non Commercial–No Derivatives)

Disclosure: If you purchase a product through this site, I may earn a commission which will help to pay for the site, the associated Meetup group, and the resources to support the blog.

Note: The Content of this post is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.